We avoid using tertiary references. This lowers your risk for bone fractures. In addition, you should use effective birth control while youre taking Prolia. Do not stop, skip or delay taking Prolia without first talking with your doctor. Prolia Because Prolia can also cause low blood calcium, your risk may increase if you receive Prolia. Vitamin D The body needs vitamin D to absorb calcium. If you have low blood calcium, it may get worse during treatment. Can diet help improve depression symptoms? It is based on denosumab and calcium (the active ingredients of Prolia and Calcium, respectively), and Prolia and Calcium (the brand names). You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Prolia is a prescription medicine used to treat osteoporosis in women after menopause who are at high risk for fracture or cannot use another osteoporosis medicine or other osteoporosis medicines did not work well. Prolia contains the active drug denosumab, and Reclast contains the active drug zoledronic acid. The most common medications prescribed to lower cholesterol are statins. They can give you more details about this possible side effect and suggest ways to manage it. What should I know about Prolia vs. Xgeva? Youll likely receive Prolia long term if you and your doctor decide that the drug is effective and safe for you. This is because its not known if Prolia is safe to receive while breastfeeding. To learn more about this, see the How is Prolia administered? section below. Do not use denosumab if you are pregnant. Last updated on Feb 8, 2023. People need calcium for bone health and other functions. Theres no information available to know whether Prolia is passed into breast milk or if its safe to take while breastfeeding. You should also take calcium and vitamin D supplements while being Prolia side effects: What you should know - Medical And if you have osteoporosis, falling could increase your risk of fractures. Whats the Connection Between Estrogen and Osteoporosis? Prolia can also increase this risk. WebProlia is used to treat osteoporosis in women after menopause and in men, and in people What are some frequently asked questions about Prolia? Get the treatment that fits your lifestyle, Stay informed with courtesy reminders, recipes and so much more. You may take the carton out of the refrigerator and allow it to reach room temperature before the injection is given. Find out which foods can help. Your low blood calcium must be treated before you receive Prolia. Others may continue for as long as you take the drug, but they can be easily managed. Do not share this medicine with others. Prolia (denosumab) | Dosing Call your doctor at once if you have: new or unusual pain in your thigh, hip, or groin; severe pain in your joints, muscles, or bones; skin problems such as dryness, peeling, redness, itching, blisters, bumps, oozing, or crusting; or. Coming to a Cleveland Clinic location?Hillcrest Cancer Center check-in changesCole Eye entrance closingVisitation and COVID-19 information, Notice of Intelligent Business Solutions data eventLearn more. Before you start Prolia treatment, your doctor will examine the inside of your mouth. See your dentist regularly. You may have questions about Prolia and your treatment plan. Throw away a prefilled syringe after one use, even if there is still medicine left inside. This includes proper brushing, flossing, mouthwash use, and regular professional dental cleanings. Prolia Other side effects may continue for as long as you receive the medication, but they can often be relieved with other treatments. We comply with the HONcode standard for trustworthy health information. We study millions of patients and 5,000 more each day. * For more information about this side effect, see Side effect specifics below. If you keep this medicine at home, store it in the original carton in a refrigerator. If you develop high cholesterol with Prolia, your doctor can guide you on which treatment options are right for your condition. Learn more about the unique risk factors for osteoporosis in, Osteoporosis weakens bones, which leads to breaks in the hips, wrists, and spine. In this article well discuss the uses, side effects, safety precautions, and other important information about Prolia. Do not take this medicine with any of the following medications: This medicine may also interact with the following medications: This list may not describe all possible interactions. Doctors sometimes prescribe Prolia to treat osteoporosis and bone thinning. What should I know about Prolia vs. Evenity? Youll receive Prolia doses from a healthcare professional. Courtney Sullivan, Certified Yoga Instructor, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT. Nausea can sometimes be a symptom of severe constipation. Theyll discuss with you other treatments to help protect you from fractures and bone loss. These can include tingling or numbness in the hands, feet, and face. Calcium and Vitamin D: A major role of vitamin D is to help the body absorb calcium and maintain bone density. While youre receiving Prolia treatment, your doctor will monitor your cholesterol levels with regular blood tests. Although very rare, Prolia can cause serious dental problems and jaw-related side effects. Patients in the study may take other drugs besides Prolia and Calcium. Here are a few questions to consider asking your doctor: You can also learn more about osteoporosis treatment options here. But before taking Prolia, be sure to tell your doctor about all medications you take (including prescription and over-the-counter types). Continue reading, While there are no known drug interactions between Prolia (generic name: denosumab) and alcohol, but you should check with your doctor first before you drink. Hair loss with Prolia was reported after the drugs initial studies were done and it was approved for use. Prolia works by blocking osteoclasts (certain bone cells) from breaking down bone tissue in your body. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Learn about the highest quality calcium supplements here. (To learn more, see the Precautions for Prolia section below.). We do not endorse non-Cleveland Clinic products or services. * Sex and gender exist on spectrums. Medically reviewed by Sanjai Sinha, MD. Calcium Supplements Prolia is used in adults to treat osteoporosis or bone loss in people who: who cannot use another osteoporosis medicine or these medicines did not work well. in your skin, lower stomach area (abdomen), bladder, or ear may happen. If you have any questions about Prolias side effects, talk with your doctor. Symptoms may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums. See what this means for you in the chart below. Prolia is a prescription medicine used to treat osteoporosis in women after menopause who are at high risk for fracture If your Prolia treatment is stopped, talk to your doctor about other medicine that By stopping RANKL from binding to its receptor Prolia reduces bone breakdown, bone loss, bone pain, and other bone complications. Having a tooth extraction while youre using Prolia may increase your risk for these side effects. It works with your immune system to help prevent bone loss. If your pain becomes severe, your doctor may recommend other treatment options to replace Prolia. Over time, Prolia can reduce bone loss and make your bones stronger. Prolia pregnancy and breastfeeding warnings. Below are commonly used dosages, but the dosage you receive will be determined by your doctor. Visit www.fda.gov/medwatch, orcall1-800-FDA-1088. A severe jawbone problem called osteonecrosis has rarely been reported with Prolia. If you have bothersome or severe side effects or other problems while taking Prolia and need to stop the medication, your doctor will monitor your bone mineral density. Are there lifestyle changes that can help my osteoporosis. Based on your dental history, your doctor can discuss with you the risks of using Prolia. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The risk is highest in people with cancer, blood cell disorders, pre-existing dental problems, or people treated with steroids, chemotherapy, or radiation. It is often used in osteoporosis. Some reports may have incomplete information. Prolia is a prescription medicine used to treat bone loss in men who are at high risk for fracture receiving certain treatments Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Your risk for having more than 1 broken bone in your spine is increased if you have already had a broken bone in your spine. Youll receive Prolia doses from a healthcare professional. Prolia is used to treat osteoporosis in women after menopause and in men, and in people who are taking corticosteroids for 6 months or more. If youre concerned about unexplained weight gain while using Prolia, talk with your doctor. * Sex and gender exist on spectrums. These factors include what your insurance plan covers. kidney disease (or if you are on dialysis); a weak immune system (caused by disease or by using certain medicines); hypoparathyroidism (decreased functioning of the parathyroid glands); any condition that makes it hard for your body to absorb nutrients from food (malabsorption); if you are scheduled for a dental procedure; if you cannot take daily calcium and vitamin D; or. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Some examples are atorvastatin (Lipitor) and rosuvastatin (Crestor). If youve noticed hair loss since starting Prolia treatment, talk with your doctor. Prolia also has other uses, which are described in the next section below. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. You do not give Prolia to yourself. Bone density decreases with time, and some people have a risk of developing weak or brittle bones. The drug may increase the risk of pregnancy loss. If you dont understand something related to your condition or treatment, ask your doctor to explain it to you. Use of the terms female and male in this article refers to sex assigned at birth. Other drugs may interact with denosumab, including prescription and over-the-counter medicines, vitamins, and herbal products. To date, the consensus is that there has been no proven risk of increased cardiovascular risk with intake of calcium supplements. Doing so will help you avoid the risk for a low calcium level during treatment.
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